Methylfolate Plus™ supplies folate, in the active form of (6S)-5-Methyltetrahydrofolic acid, glucosamine salt. Methylfolate is a highly absorbable, activated form of folate, which does not require enzymatic conversion to 5-methylfolate in the body. The glucosamine salt form utilized in Methylfolate Plus™ is more stable than other forms of methylfolate often used. Folate deficiency is one of the most common vitamin deficiencies. In individuals with homozygous (TT) or heterozygous (CT) genetic predisposition, eating folate-rich foods may not provide the recommended daily dosage of folate; thus the need for supplementation. By providing 5-methylfolate directly, Methylfolate Plus™ and may have benefits for those who do not produce enough 5-methylfolate in response to folic acid supplementation. Each serving (½ tablet) of Methylfolate Plus™ supplies 400 mcg of folate as 5-methylfolate, combined with 25 mcg of vitamin B12 as methylcobalamin in our biologically active, phytochemically rich vegetable culture base.